. 2016 Nov 8;14:16. doi: 10.1186/s12953-016-0105-x

Table 3.

Summary table showing significantly up-regulated or down-regulated proteins of structural constituent of SOL muscle in Daurian ground squirrels identified by iTRAQ

Acc no. (NCBI)	Prot name [Ictidomys tridecemlineatus]	MW (Da)	Peptide	Score	60-d hibernation vs pre-hibernation		Post-hibernation vs pre-hibernation		Post-hibernation vs 60-d hibernation
Acc no. (NCBI)	Prot name [Ictidomys tridecemlineatus]	MW (Da)	Peptide	Score	Fold change	Sig	Fold change	Sig	Fold change	Sig
Up-regulated proteins
gi\|532098453	small muscular protein isoform X2	12381	3	504	1.238	*	1.392	*
gi\|532095619	cofilin-1	26628	7	639	1.239	*	1.535	*
gi\|532065022	tubulin polymerization-promoting protein family member 3	27600	2	147	1.607	*	1.481	*
gi\|532085001	myosin light chain 4 isoform X2	27241	6	968	1.434	*	1.579	*
gi\|532097561	myelin basic protein	44089	2	69	1.456	*
gi\|532069819	nebulin-related-anchoring protein	245551	22	744	1.211	*
gi\|532094579	myosin-2	244418	102	66551	2.135	*
gi\|532087098	PDZ and LIM domain protein 3 isoform X1	45822	12	3700	1.304	*
gi\|532062716	troponin C	22795	11	5693	1.358	*
gi\|532080240	vimentin	54132	26	3859	1.211	*			1.828	*
gi\|532089364	myosin-binding protein H	60653	11	835			1.696	*
gi\|532081847	zyxin	72401	2	97			1.371	*
gi\|532111896	tubulin alpha-8 chain isoform X1	60805	15	2177			1.355	*
gi\|532063429	F-actin-capping protein subunit beta isoform X2	36610	11	763			1.219	*
gi\|532074211	nidogen-2 isoform X1	165553	7	164			1.467	*
gi\|532076843	myozenin-3	30065	6	801			1.401	*
gi\|532100104	myosin light polypeptide 6 isoform X1	20132	8	2096			1.576	*
gi\|532099239	moesin-like	87289	14	565			1.248	*
gi\|532103138	myosin regulatory light chain 12B	24691	6	374			1.771	*
gi\|532081115	talin-1	321070	21	790			1.288	*	1.302	*
gi\|532088445	myosin regulatory light polypeptide 9 isoform X1	24375	5	323			1.68	*
gi\|532095126	PDZ and LIM domain protein 7	60050	6	361			1.653	*
gi\|532111349	ankyrin-1 isoform X1	242338	33	1740			2.69	*
gi\|532098546	tubulin beta-5 chain-like	46713	12	1245			1.367	*
gi\|532061621	annexin A2	49151	21	2021			1.502	*
gi\|532068053	myocilin	59868	4	159			2.837	*
gi\|532100974	neurofilament heavy polypeptide	158649	7	679			1.55	*
gi\|532110489	neurofilament medium polypeptide	123496	7	571			1.677	*
gi\|532089731	tubulin alpha-4A chain	56718	18	3110			1.396	*
gi\|532089733	tubulin alpha-1D chain-like	57019	18	3316			2.103	*
gi\|532063781	protein 4.1 isoform X1	120337	9	505			2.552	*
gi\|532111734	alpha-actinin-4 isoform X1	125310	18	2664			1.228	*
gi\|532072736	beta-adducin isoform X1	100809	3	84			1.759	*
gi\|532083652	tubulin beta-2A chain isoform X1	56576	21	2455			1.637	*	1.687	*
gi\|532081219	tropomodulin-1	49085	4	141					1.509	*
gi\|532102653	tubulin beta-4B chain isoform X1	55122	22	3594					1.25	*
gi\|532062201	fibrillin-1	340347	14	616					1.685	*
Down-regulated proteins
gi\|532094519	myosin-3	287961	49	33292	0.587	*	0.399	*	0.758	*
gi\|532085261	transgelin isoform X2	28099	11	691	0.784	*
gi\|532062201	fibrillin-1	340347	14	616	0.534	*
gi\|532072041	telethonin	21240	8	817	0.811	*
gi\|532081219	tropomodulin-1	49085	4	141	0.701	*
gi\|532103167	actin	48418	23	58752			0.823	*	0.806	*
gi\|532059726	xin actin-binding repeat-containing protein 2-like	476702	6	84			0.774	*
gi\|532069819	nebulin-related-anchoring protein	245551	22	744			0.747	*
gi\|532094510	myosin-13	285781	37	26764			0.478	*
gi\|532077683	kelch-like protein 41	85237	21	1666			0.772	*
gi\|532097391	supervillin	300575	12	302			0.789	*
gi\|532112765	cytoplasmic dynein 1 heavy chain 1	620997	16	383			0.807	*
gi\|532113339	obscurin, partial	143269	19	783			0.829	*
gi\|532112836	flotillin-1	56752	3	161			0.806	*
gi\|532062845	filamin-B	333949	10	1568			0.743	*
gi\|532094579	myosin-2	244418	102	66551					0.482	*

Acc no. (Accession number), Prot name (protein name), MW (Molecular mass), Peptide (number of peptides matched), Score (Mowse score), Sig (*P-value < 0.05 was considered statistically significant)