Table 2.
Yield of smear microscopy versus Xpert among culture confirmed tuberculosis patients (n =96)
| Xpert | Sensitivity of SM % (95 %, CI) | Incremental sensitivity of Xpert % (95 %,CI) | |||
|---|---|---|---|---|---|
| Positive | Negative | ||||
| Overall SM at all HF n = 96 |
positive | 46 | 3 | 51.0 (40.6–61.4) | 32.3 (23.1–42.6) |
| negative | 31 | 16 | |||
| SM in all HIV positive n = 28 |
positive | 10 | 1 | 39.3 (21.5–59.4) | 35.7 (18.6–55.9) |
| negative | 10 | 7 | |||
| SM in all HIV negative n = 68 |
positive | 36 | 2 | 55.9 (43.3–67.9) | 30.9 (20.2–43.3) |
| negative | 21 | 9 | |||
| SM at all PL n = 76 |
positive | 34 | 3 | 48.7 (37.0–60.4) | 32.9 (22.5–44.6) |
| negative | 25 | 14 | |||
| SM at all IL n = 20 |
positive | 12 | 0 | 60.0 (36.1–80.9) | 30.0 (11.9–54.3) |
| negative | 6 | 2 | |||
| SM at ZN PL n = 49 |
positive | 24 | 3 | 55.1 (40.2–69.3) | 32.7 (19.9–47.5) |
| negative | 16 | 6 | |||
| SM at LED-FM PL n = 27 |
positive | 10 | 0 | 37.0 (19.4–57.6) | 33.3 (16.5–54.0) |
| negative | 9 | 8 | |||
| SM at ZN IL n = 12 |
positive | 7 | 0 | 58.3 (27.7–84.8) | 25.0 (5.5–57.2) |
| negative | 3 | 2 | |||
| SM at LED-FM IL n = 8 |
positive | 5 | 0 | 62.5 (24.5–91.5) | 37.5 (8.5–75.5) |
| negative | 3 | 0 | |||
LED-FM light emitting diode fluorescence microscopy; ZN Ziehl Nelsen Xpert: Xpert MTB/RIF test; HIV human immunodeficiency virus; CI confidence interval; SM smear microscopy; IL intermediate laboratories; PL peripheral laboratories; SM smear microscopy