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. 2016 Jul 26;17(1):361–374. doi: 10.1080/14686996.2016.1200948

Figure 6.

Figure 6.

(a) Flow cytometry histograms of normal human skin fibroblasts treated with HF680–4.1HEE-PRX (0.5 mM of β-CD) for various time periods. (b) Time course of the fluorescence intensities of normal human skin fibroblasts treated with HF680-HEE-PRXs (HF680–4.1HEE-PRX: closed squares, HF680–5.4HEE-PRX: open circles, HF680–6.4HEE-PRX: closed triangles, HF680–7.6HEE-PRX: open diamonds) (0.5 mM of β-CD). (c) Effect of endocytosis inhibitors (dynasore for clathrin-mediated endocytosis, genistein for caveolae-mediated endocytosis, and amiloride for macropinocytosis) on the fluorescence intensities of HF680–4.1HEE-PRX-treated normal human skin fibroblasts after 6 h. The data are expressed as the mean ± SD (n = 3) (****p < 0.001 vs. untreated cells).