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Hematoxylin and eosin staining of kidney tissues at different time points in the different groups of rats. (A) Control; (B) high fat diet+FK506 (0.15 mg/kg/day) for 2 weeks; (C) high fat diet+FK506 (0.15 mg/kg/day) for 4 weeks; (D) high fat diet+FK506 (0.15 mg/kg/day) for 8 weeks. Original magnification, ×400. FK506, tacrolimus.
