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. 2016 Sep 26;14(5):4198–4208. doi: 10.3892/mmr.2016.5784

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Copyright: © Xie et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Cap and DHC inhibit the growth of U251 human glioma tumor xenografts in a BALB/c nude mouse xenograft model. (A) Average tumor volume, measured using vernier calipers. Data are presented as the mean ± standard error (n=6–7 mice per group). (B) Average wet weight of tumors following 3 weeks of treatment. Data are presented as the mean ± standard error (n=6–7 mice per group). *P<0.05, **P<0.01 vs. control. (C) Morphological changes in tumors, visualized by hematoxylin and eosin staining. (D) Immunohistochemical analysis of cytochrome c immunoreactivity in dissected tumors. Cap, capsaicin; DHC, dihydrocapsaicin.