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Potential mechanisms of cell proliferation stimulated by TiO2-PEG NPs. One hypothesis holds that insertion of TiO2-PEG NPs between the lipid bilayer changes the structure of the cell membrane, narrowing the space between HGFRs and leading to the formation of HGFR aggregates. The other hypothesis holds that TiO2-PEG NPs bind adjacent HGFRs together; ‘n’ indicates the number of HGFRs.
