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. 2016 Oct 5;14(5):4521–4528. doi: 10.3892/mmr.2016.5809

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Copyright: © Choi et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Effect of Centella asiatica on DMN-induced inflammatory cytokines and mediators in serum. The animals (n=8/group) were orally administrated with Centella asiatica at 100 or 200 mg/kg. DMN in D.W was used as a vehicle control. Saline in D.W was used as a negative control. Values are presented as the mean ± standard error of the mean. **P<0.01 and *P<0.05, compared with the negative control; ^##P<0.01 and ^#P<0.05, compared with the vehicle control. DMN, dimethylnitrosaminel TNF, tumor necrosis factor-α;, TNF-α; IL, interleukin; IFN-γ, interferon-γ; GM-CSF, granulocyte/macrophage colony-stimulating factor; D.W, distilled water.