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. 2016 Oct 13;14(5):4581–4592. doi: 10.3892/mmr.2016.5851

Table II.

The association of MCM2 and TIP30 expression with the clinicopathological characteristics of SC/ASC.

MCM2 TIP30


Clinicalpathological characteristics Total no. Pos no. (%) χ2 P-value Pos no. (%) χ2 P-value
Sex 0.090 0.765 1.565 0.211
  Male 19 9 (47.4) 12 (63.2)
  Female 27 14 (51.9) 12 (44.6)
Age (years) 0.357 0.550 0.270 0.603
  ≤45 3 1 (33.3) 2 (66.7)
  >45 43 22 (51.2) 22 (51.2)
Pathological type 0.354 0.552 2.333 0.127
  SC 26 14 (53.8) 11 (42.3)
  ASC 20 9 (45.0) 13 (65.0)
Differentiation 7.167 0.028 3.753 0.153
  Well 16 6 (37.5) 10 (62.5)
  Moderately 24 11 (45.8) 13 (54.2)
  Poorly 6 6 (100.0) 1 (16.7)
Tumor mass size 5.662 0.017 7.389 0.007
  ≤3 cm 20 6 (30.0) 15 (75.0)
  >3 cm 26 167 (65.4) 9 (34.6)
Gallstones 0.365 0.546 0.708 0.400
  No 18 10 (55.6) 8 (44.4)
  Yes 28 13 (46.4) 16 (57.1)
TNM stage 10.943 0.004 9.936 0.008
  I+II 12 3 (25.0) 10 (83.3)
  III 20 8 (40.0) 11 (55.0)
  IV 14 12 (85.7) 3 (21.4)
Lymph metastasis 4.572 0.032 6.379 0.012
  No 17 5 (29.4) 13 (76.5)
  Yes 29 18 (62.1) 11 (37.9)
Invasion 6.133 0.013 12.270 0.000
  No 16 4 (25.0) 14 (87.5)
  Yes 30 19 (63.3) 10 (33.3)
Surgery 7.365 0.025 9.296 0.00
  Radical 14 3 (21.4) 11 (78.6)
  Palliative 18 10 (55.6) 10 (55.6)
  Biopsy 14 10 (71.4) 3 (21.4)

MCM2, minichromosome maintenance complex component 2; TIP30, HIV-1 tat interactive protein 2; SC, squamous cell; ASC, adenosquamous carcinoma.