Figure 1.

Serological and histological alterations of mice following 12 weeks of CCl₄ injection. Mice were intraperitoneally injected with CCl₄ repeatedly for 12 weeks to induce liver fibrosis. (A) Histological changes of the liver tissues of CCl₄-treated mice. Upper panels, HE staining; lower panels, Masson's trichrome staining. Magnification, ×100. (B) Serum ALT levels and (C) ALB levels. Data are presented as the mean ± standard deviation; **P<0.01. HE, hematoxylin and eosin; ALT, alanine aminotransferase; ALB, albumin.