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. 2016 Oct 12;14(5):4692–4698. doi: 10.3892/mmr.2016.5839

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Copyright: © Ju et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Effect of MSJ administration on the serum testosterone production and mRNA level of 5α-reductase 2 in prostate tissues of BPH-induced rat models. (A) The serum concentrations of testosterone were determined using ELISA. (B) The mRNA expression of 5α-reductase 2 in prostate tissue was analyzed by reverse transcription-quantitative polymerase chain reaction for the Con, BPH-induced, Fina and MSJ groups. The data are presented as the mean ± standard error of the mean of 6 rats per group (^#P<0.05 vs. Con group; ***P<0.001 vs. BPH group). BPH, benign prostatic hyperplasia; Fina, BPH-induced group treated with finasteride 5 mg/kg/day; MSJ, BPH-induced group treated with musulju 200 mg/kg/day; Con, control.