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. 2016 Sep 12;30(12):4192–4201. doi: 10.1096/fj.201600144RR

Figure 2.

Figure 2.

Confocal microscopy of elastase-perfused aortas in animals treated with vehicle only (A) and in RvD2-treated animals (B) at d 14. Evident was marked increase in M2 macrophage marker (Arg-1, arrows) in RvD2-treated animals. Confocal images were scored by 2 independent observers for M1 (MCP-1) and M2 (Arg-1) staining density as follows: 1 = none, 2 = mild staining, 3 = moderate staining, 4 = extensive staining. RvD2-treated animals had significantly higher M2 scores (P < 0.0001) and lower M1 scores (P = 0.03) compared to nontreated animals.