TABLE 2.

Plasma NDE levels of total synapsin 1 protein and P-S9-synapsin 1

Protein	FTC	FTD	AC	AD
Synapsin 1 protein (pg/ml)	2295 ± 138	7781 ± 1379**	2048 ± 219	1058 ± 99**
P-S9-synapsin 1 (OD450 nm/ng synapsin 1)	0.511 ± 0.050	0.118 ± 0.021**	0.545 ± 0.081	0.270 ± 0.049*

Each value is the mean ± sem for levels of the 16 patients with FTD and controls (FTC) or 12 patients with AD and controls (AC) in Fig. 1. Group differences were determined by an unpaired Student’s t test. *P < 0.01; **P < 0.001.