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. Author manuscript; available in PMC: 2016 Nov 9.
Published in final edited form as: Drug Discov Today Dis Models. 2008 Winter;5(4):299–309. doi: 10.1016/j.ddmod.2009.07.002

Figure 1.

Figure 1

Enzyme-catalyzed reaction. The enzyme, E, converts the substrate, S, to the product, P. The enzyme and substrate form an intermediate complex, ES, which can dissociate back to E and S or form P and free the enzyme, E. This model treats the production of P from the ES complex as an irreversible reaction because the reversible reaction rate may be negligible.