Activation of an RTN neuron by sciatic nerve stimulation. A: sciatic nerve stimulation during period of low eeCO2. From top to bottom: eeCO2, rectified/smoothed PND, PND rate (bursts/min), BP, RTN unit, and unit's discharge rate. Contra- and ipsilateral sciatic nerve stimulated at 0.5 Hz. B, from top to bottom: higher-resolution excerpt of the unit's response to contralateral sciatic nerve stimulation (stimuli at arrowheads), poststimulus time histogram (stimuli delivered at time 0; stimulus artifacts eliminated) of the neuronal activity showing bimodal activation (latencies: 40 ms for early peak, 100 ms for late peak), and poststimulus time histogram of the onset of the PND evoked by nerve stimulation. C: response of the same unit to stimulation of the ipsilateral sciatic nerve (presentation as in B; 45-ms and 95-ms latency for early and late peaks, respectively).