Table 1.
Electrophysiological properties for developing CA1 pyramidal neurons
P5–10 | P15–20 | P25–30 | P60–100 | P Value | |
---|---|---|---|---|---|
Resting membrane potential, mV | −73.4 ± 0.5 | −72.7 ± 0.5 | −73.3 ± 0.4 | −73.8 ± 0.6 | 0.6 |
Input resistance, MΩ | 318.3 ± 11.1* | 222.9 ± 8.9† | 160.7 ± 7.6‡ | 156.2 ± 4.1‡ | <0.0001 |
Spike amplitude, mV | 75.5 ± 1.3* | 83.0 ± 2.5† | 91.8 ± 1.9‡ | 82.5 ± 1.6† | <0.0001 |
Values are means ± SE at postnatal days 5–10 (P5–10; n = 62), P15–20 (n = 35), P25–30 (n = 33), and P60–100 (n = 35). P values were determined by 1-way ANOVA. *†‡Different symbols indicate statistically significant differences among data sets (Tukey's post hoc test).