Table 2. Known attributes of skin aging are significantly different between skin youthfulness (SY) and non-SY group phenotype.

Parameter	SY group (n = 12)	Non-SY group (n = 33)	P
Mean skin age score (SAS), years (SD)	61.0 (5.0)	81.0 (8.0)	2.34x10-11
Mean percentile VISIA computer software wrinkle score (SD)	93.0 (10.6)	73.0 (22.0)	0.00038
Mean epidermal thickness, by cell layers (SD)	12.50 (1.96)	9.70 (2.91)	0.0082

Assessments were made by dermatologists’ clinical evaluation, computer based complexion analysis software, and histological examination.