Table 3. Additional individual SY genes with interesting themes or function.

Aging related pathway	Selected references	Number of genes	SY Genes (bold font indicates increased levels in SY, non-bold font indicates decreased transcript levels)
Glycoprotein biosynthetic process or glycoprotein metabolic process	Huang et al., 2009, accessed on DAVID Bioinformatics Resources 6.7	158 and202 respectively (GO)	• PHLDA1 • NDST2 • ST6GAL1 • DPM3 • GCNT1
Hyaluronan synthesis pathway	Gorbunova et al., 2014	N/A	HAS2-AS1
NFkB targets	Adler et al., 2007	610 (MSigDB)	• NTRK3 • PCDH10 • OGG1
Broadband light related rejuvenation genes	Chang et al., 2013	3,531 (Chang et al., 2013)	• CFB • LOC283335 • SH3BP4 • MRPS12 • ACVRL1 • PIWIL4 • DPM3 • NEK1 • ECE2 • EML3 • BAMBI • FAM189A2	• DGKD • SOD2 • STXBP1 • LAGE3 • NTRK3 • CCDC88A • RASSF4 • PLEKHJ1 • PADI2 • UTP11L • BAG5 • CDT1

SY transcripts with known association to aging function, out of the 114 SY transcripts identified by 3’-seq that are not included in the Gene Sets depicted in Fig 5.