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. 2016 Nov 9;11(11):e0165081. doi: 10.1371/journal.pone.0165081

Table 1. Maternal characteristics of the sample, Ukraine, 2006–2011.

Variable HEa (N = 22) HEua (N = 23) UE (N = 23) p-value
Mother’s age at enrollment (momage) 26.95 ±6.00 24.04 ± 4.40 26.30 ± 4.70 0.1377a
Gestational age at enrollment 18.60 ± 4.83 19.13 ± 5.90 17.94 ± 6.38 0.5051a
Recruitment site Khmelnytsky 50.0% (11) 17.4% (04) 21.7% (05) 0.0467b
Rivne 50.0% (11) 82.6% (19) 78.3% (18)
Marital status Married or cohabiting 72.7% (16) 91.3% (21) 100.0% (23) 0.0093 b
Single/separated/divorced 27.3% (06) 8.7% (02) 0.0% (00)
Education Less than high school 13.6% (03) 8.7% (02) 0.0% (00) 0.0246 b
High school or equivalent 54.5% (12) 60.9% (14) 30.4% (07)
Some college or higher 31.8% (07) 30.4% (07) 69.6% (16)
Socio-economic category (sescat, Hollingshead score) 55–66 9.1% (02) 8.7% (02) 17.4% (04) 0.0315 a
40–54 13.6% (03) 17.4% (04) 43.5% (10)
30–39 45.5% (10) 43.5% (10) 21.7% (05)
20–29 4.5% (01) 26.1% (06) 17.4% (04)
08–19 27.3% (06) 4.3% (01) 0.0% (00)
Gravidity >1 54.5% (12) 34.8% (08) 56.5% (13) 0.3032b
1 45.5% (10) 65.2% (15) 43.5% (10)
Parity >0 40.9% (09) 30.4% (07) 47.8% (11) 0.4767b
0 59.1% (13) 69.6% (16) 52.2% (12)
Body Mass Index 22.01 ± 4.55 22.75 ± 3.98 21.18 ± 3.05 0.3701a
Smoking status (smokstat) Current Smoker 31.8% (07) 21.7% (05) 0.0% (00) 0.0001 b
Never Smoked 22.7% (05) 21.7% (05) 95.7% (22)
Quit after realized pregnant 36.4% (08) 34.8% (08) 0.0% (00)
Quit Before Pregnancy 9.1% (02) 21.7% (05) 4.3% (01)
Number of cigarettes per day during pregnancy 2.50 ±4.34 0.87 ±2.26 0.00 ±0.00 0.0142 a
Multi-Vitamins after enroll No 36.4% (08) 39.1% (09) 43.5% (10) 0.2216a
Yes 63.6% (14) 60.9% (14) 56.5% (13)
Multi-vitamins pre-enroll No 36.4% (08) 21.7% (05) 26.1% (06) 0.5392a
Yes 63.6% (14) 78.3% (18) 73.9% (17)
Gestational age at 1st blood draw 19.09 ± 5.18 18.30 ± 5.82 18.00 ± 4.45 0.7241a
Gestational age at 2nd blood draw 32.95 ± 2.77 33.52 ± 2.50 32.26 ± 3.15 0.2238a
AAD0: Absolute ounces of alcohol per day at time of conception 0.69 ±0.65 0.50 ±0.27 0.00 ±0.00 0.0001 a
AADD0: Absolute ounces of alcohol per drinking day at time of conception 1.72 ±1.33 1.50 ±1.05 0.00 ±0.00 0.0001 a
AADXP: absolute ounces of alcohol per day in two weeks prior to enrollment 0.09 ±0.17 0.03 ±0.06 0.00 ±0.00 0.0003 a
AADDXP: Absolute ounces of alcohol per drinking day in two weeks prior to enrollment 0.55 ±0.79 0.24 ±0.35 0.00 ±0.00 0.0002 a

x ± y represents the mean ± standard deviation, (n) = sample size. P-values in Bold are statistically significant.

a Kruskal-Wallis Rank Sum Test

b Fisher's Exact Test