Table 1. Demographic and clinical variables.
22q11DS (n = 18) | UHR (n = 18) (APS:16/BLIPS:2 /Fam: 0) | Controls (n = 24) | stats | p | |
---|---|---|---|---|---|
Age (sd) in years | 25 (2.6) | 22.7 (3.6) | 23.4 (3.2) | F = 2.42 | 0.09 |
Gender male/female | 9/9 | 8/10 | 14/10 | X2 = 0.82 | 0.66 |
PANSS positive (M/sd) | 8.8 (2.6) | 11.3 (2.4) | t = 2.92 | 0.006 | |
PANSS negative (M/sd) | 12.6 (4.6) | 11.8 (5.7) | t = 0.48 | 0.63 | |
PANSS general (M/sd) | 25.3 (7.1) | 45.1 (12.1) | t = 6.02 | 0.001 | |
Psychosis yes/no | 8/10 | ||||
Antipsychotic medication (yes/no) | 8/10 | ||||
Congenital heart disease yes/no | 8/10 |
PANSS: Positive and Negative Syndrome Scale; UHR: ultra-high risk subjects; 22q11DS: 22q11.2 deletion syndrome subjects; APS: attenuated psychotic symptoms; BLIPS: brief limited psychotic symptoms; Fam: first degree relative with psychotic disorder; M: mean; sd: standard deviation.