Table 1. Demographic details of the 10 patients included in the whole exome sequencing study.
| Sample ID | Histology | FIGO stage | Age (yrs.) | Disease status | HPV genotype* | Viral genome status# | Integration site# |
|---|---|---|---|---|---|---|---|
| 1123 | SCC | IIIB | 40 | NED | 16 | Integrated | Unknown |
| 999 | SCC | IIIB | 49 | NED | 16 | Integrated | 4q13.3 |
| 938 | SCC | IIIB | 50 | LR + DM | 16, 18 | Not known | |
| 1099 | SCC | IIIB | 38 | NED | 16 | Not known | |
| 1103 | SCC | IIIB | 50 | DM | 16 | Not known | |
| 755 | SCC | IIIB | 44 | LR | 16 | Integrated | 3q23 |
| 785 | SCC | IIIB | 43 | LR | 16, 18 | Integrated | 3q23, 20q11.21 |
| 937 | SCC | IIIB | 50 | LR | Not detected | - | - |
| 1023 | SCC | IIIB | 16 | Not known | |||
| 1094 | SCC | IIIB | 58 | DM | 16 | Integrated | 13q |
Key: SCC- Squamous cell carcinoma; NED-No Evidence of Disease; LR-Local Recurrence; DM-Distant Metastasis; HPV-Human Papilloma Virus
*HPV was determined by Luminex Bead Array and HPV type specific PCR
#Viral genome status and integration site were determined by APOT assay as described in Ref. 8