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. Author manuscript; available in PMC: 2016 Nov 9.
Published in final edited form as: Clin Exp Neuroimmunol. 2014 Apr 22;5(3):290–303. doi: 10.1111/cen3.12107

Figure 6.

Figure 6

(a) The M23-aquaporin-4 (AQP4) isoform gives a brighter signal than the M1 isoform by cell-based assay (CBA). (b) N-terminal enhanced green fluorescent protein (EGFP)-tagged M23 AQP4 assay is less sensitive than untagged M23 AQP4 assay, by end-point titration. (c) There is a wide variation in the serum volume and concentrations used in assays to detect AQP4-IgG. ELISA, enzyme-linked immunosorbent assay; FACS, flow cytometry; FIPA, fluorescence immunoprecipitation assay; IIF, indirect immunofluorescence; RIPA, radioimmunoprecipitation assay.