Wide-field OCME of a freshly excised malignant tumor. (a) Wide-field en face OCME overlay on OCT of the entire sample, measuring 47.5 × 47.5 mm. (b) Histology, co-registered with OCT and OCME image. (The white horizontal artifact at top is due to stitching images taken from tissue in two histology cassettes.) (c) En face OCT image showing a 1.6× magnification of the boxed region in (a). (d) Corresponding en face OCME overlay. A, adipose; C, cassette stitching artifact; D, dense tissue; NC, non-contact; S, stroma; and T, tumor.