. Author manuscript; available in PMC: 2017 May 1.

Published in final edited form as: J Geriatr Psychiatry Neurol. 2016 Feb 9;29(3):120–125. doi: 10.1177/0891988715627016

Table 2B.

Unadjusted and Adjusted Odds Ratios and 95% Confidence Interval of the Association Between Alzheimer Dementia and Diabetes Mellitus.^a,^b,^c

Variables	Alzheimer Dementia
Variables	Unadjusted OR (95% CI)	Model 1 OR (95% CI)	Model 2 OR (95% CI)	Model 3 OR (95% CI)
DM	0.73 (0.72–0.74)^d	0.87 (0.86–0.87)^d	0.87 (0.86–0.88)^d	0.57 (0.56–0.58)^d
Age		1.09 (1.09–1.09)^d	1.09 (1.09–1.09)^d	1.09 (1.09–1.09)^d
Gender
Male		Ref	Ref	Ref
Female		1.19 (1.18–1.20)^d	1.17 (1.16–1.17)^d	1.17 (1.16–1.18)^d
Race
White		Ref	Ref	Ref
Black		1.44 (1.38–1.51)^d	1.45 (1.39–1.51)^d	1.49 (1.43–1.55)^d
Hispanic		1.27 (1.19–1.36)^d	1.27 (1.19–1.36)^d	1.27 (1.18–1.36)^d
Other		1.00 (0.94–1.08)^d	1.00 (0.94–1.07)	1.01 (0.94–1.08)
Stroke			1.59 (1.54–1.65)^d	1.56 (1.50–1.61)^d
Depression			1.79 (1.76–1.83)^d	1.83 (1.80–1.87)^d
Hypertension			0.89 (0.88–0.90)^d	0.87 (0.86–0.88)^d
Chronic obstructive pulmonary disease (COPD)			0.73 (0.71–0.74)^d	0.73 (0.71–0.74)^d
Interaction of DM and age				1.61 (1.58–1.64)^d
Interaction of DM and race
DM–Black				0.94 (0.92–0.96)^d
DM–Hispanic				1.01 (0.98–1.05)
DM–other				1.00 (0.96–1.04)
Interaction of DM and depression				0.90 (0.88–0.92)^d
Interaction of DM and stroke				1.09 (1.05–1.14)^d
Interaction of DM and hypertension				1.09 (1.08–1.11)^d

Abbreviations: Ref, reference category; OR, odds ratio; CI, confidence interval; DM, diabetes mellitus.

Model 1: DM and demographics (age, gender, and race/ethnicity).

Model 2: DM and demographics (age, gender, and race/ethnicity), and comorbidities (stroke, depression, hypertension, and COPD).

Model 3: DM and demographics (age, gender, and race/ethnicity), comorbidities (stroke, depression, hypertension, and COPD), and interaction terms.

P < .05.