Table 1.
Zoledronic acid (n=122) | Placebo (n=111) | |
---|---|---|
Age at randomization, years | 74.2±5.6 | 74.3±6.4 |
Age at time of menopause, years | 48.2±5.8 | 46.8±5.7 |
Race | ||
Caucasian | 90 (73.8) | 89 (80.2) |
Asian | 32 (26.2) | 22 (19.8) |
Body mass index, kg/m2 | 25.0±4.3 | 24.8±3.9 |
Prior bisphosphonate usage | ||
Yes | 108 (88.5) | 91 (82.0) |
No | 14 (11.5) | 19 (17.1) |
Missing | 0 | 1 (0.9) |
Baseline vertebral fracture | ||
Yes | 68 (55.7) | 63 (56.8) |
No | 54 (44.3) | 48 (43.2) |
Patients with three infusions | 92 (75.4) | 83 (74.8) |
Corrected BMD, g/cm3 | ||
Lumbar spine | 0.807±0.119 (n=67) | 0.802±0.137 (n=68) |
Femoral neck | 0.565±0.081 (n=97) | 0.560±0.083 (n=86) |
Total hip | 0.681±0.101 (n=97) | 0.672±0.097 (n=86) |
Data are expressed as n (%) or mean+SD