Figure 1.

The role of MDSCs in immune tolerance induction of transplant. The crosstalk between MDSCs and immune cells such as NK cells, DCs, Tregs, macrophages, and NKT cells contributes to the establishment of immune tolerance in kidney transplant, skin transplant, pancreatic islet transplant, cardiac transplant, and GVHD in HSC transplant (NK cells: natural killer cells; DCs: dendritic cells; Tregs: regulatory T cells; NKT cells: natural killer T cells; GVHD: graft-versus-host disease; HSC: hematopoietic stem cell).