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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Virology. 2016 Sep 12;499:9–22. doi: 10.1016/j.virol.2016.08.031

Fig. 7. Role of soluble TGF-β in B-cell suppression by M-MDSCs.

Fig. 7

Suppression of B-cell proliferation by supernate from suppressive cultures of MDSCs and B cells was assessed as in Fig. 3. Supernates were treated with increasing doses of anti-TGF-β or IgG1 control. Higher doses were tested, but did not show additional blockade and began to induce toxicity. Data shown are from a representative experiments. This pattern of results is representative of four experiments. Significance levels: **, p<0.01. p-values are versus untreated.