Fig. 6. Concentrations of IL-4 (A), IL-5 (B), IL-10 (C), and IFN-γ (D) in spleen cell culture of each group by ELISA. Systemic Th2 cytokines (IL-4 and IL-5) were significantly decreased in treatment group C than in positive control group B. However, systemic regulatory cytokine (IL-10) or Th1 cytokine (IFN-γ) did not change in treatment group C. Data are expressed as mean±standard error mean (SEM). ^*P<0.05.