Table 3. Diagnostic Sensitivities and Specificities of Advanced Imaging for AD.
| Study Subjects | Sensitivity | Specificity | |
|---|---|---|---|
| Diffusion tensor imaging | |||
| Total hippocampal volume + FA of left posterior cingulum | AD vs. controls | 88% | 94% |
| FA | AD vs. controls | 86% | 65% |
| MD | 86% | 95% | |
| MD of hippocampus and pallidum | AD vs. controls | 86.7% | 98.7% |
| Quantitative susceptibility mapping | NA | NA | |
| Magnetic transfer imaging | NA | NA |
AD = Alzheimer's disease, NA = not applicable, FA = fractional anisotropy, MD = mean diffusivity