Table 3. Associations between Presence of Spiculated Mass and Clinicopathologic Variables.
| Univariate Analysis | P | Multivariable Logistic Regression OR‡ | ||
|---|---|---|---|---|
| Spiculation | Non-Spiculation | |||
| Breast composition | 0.017 | |||
| ACR I–II* | 24 (32) | 52 (68) | 1.7 (1.26–2.33) | |
| ACR III–IV† | 45 (19) | 197 (81) | 1§ | |
| Histology | 0.082 | - | ||
| IDC | 67 (23) | 225 (77) | ||
| Others | 2 (8) | 23 (92) | ||
| Pathology grade | < 0.001 | |||
| I + II | 59 (28) | 150 (72) | 3.4 (1.32–4.25) | |
| III | 10 (9) | 98 (91) | 1§ | |
| Size | 0.302 | - | ||
| ≤ 20 mm | 37 (27) | 99 (73) | ||
| > 20 mm | 32 (22) | 114 (78) | ||
| ER | < 0.001 | |||
| + | 63 (27) | 169 (73) | 3.1 (2.03–4.53) | |
| − | 6 (7) | 79 (93) | 1§ | |
| PR | 0.001 | |||
| + | 58 (27) | 155 (73) | 2.5 (1.48–4.89) | |
| − | 11 (11) | 93 (89) | 1§ | |
| Ki67 | < 0.001 | |||
| 14% | 49 (45) | 60 (55) | 4.7 (3.3–5.28) | |
| > 14% | 20 (10) | 188 (90) | 1§ | |
| HER2 | < 0.001 | |||
| − | 66 (27) | 181 (73) | 6.3 (4.53–8.21) | |
| + | 3 (4) | 67 (96) | 1§ | |
Unless otherwise specified, data are numbers of masses, with percentages in parentheses. *Almost entirely fat or scattered fibroglandular densities, †Heterogeneously dense or extremely dense, ‡Data in parentheses are 95% confidence intervals, §Reference level in OR calculation. ACR = categories of American College of Radiology in breast composition, ER = estrogen receptor, HER2 = human epithelial growth factor receptor 2, IDC = invasive ductal carcinoma, OR = odds ratio, PR = progesterone receptor