Fig. 6.

Illustration of voxel-wise analysis of (a) Betula and (b) NCNG samples using TBSS and permutation-based testing for rs149603240. Red denotes voxels with significantly decreased FA in TC carriers compared to CC carriers of rs149603240 (P < 0.05, 2-tailed, corrected for multiple comparisons across space using 10 k permutations and TFCE), covarying for main effects of age and sex. Results from tract-based spatial statistics are superimposed on a Montreal Neurological Institute (MNI) common brain template. The numbers refer to the corresponding MNI coordinate for each axial slice. A anterior; P posterior; L left side; R right side of the brain