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Interaction between CrkII and cAbl. (A) Domain organizations of CrkII and cAbl. (Arrows) Recognition of PRMs in cAbl by the nSH3 domain of CrkII. (Gray boxes) Three PRMs in human cAbl-1A are shown with residue numbers. (B) Crystal structure of nSH3:PRM758 (Protein Data Bank (PDB): 5IH2). (Blue spheres) Backbone amide nitrogen atoms that are used for NMR CPMG-RD experiments. (Green) PRM758. To see this figure in color, go online.
