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Selective knockdown of IRF5 abolishes the induction CCR5 by super-low dose LPS monocytes co-cultured with either control or IRF5-specific siRNAs were challenged with LPS. The levels of CCR5 were measured by flow cytometry. Error bar represents SEM of three experiments. **p < 0.01, ***p < 0.001, as compared to non-treated control group, Student’s t-test.
