Figure 8.

Differential regulation of monocytes responses by TLR3 ligand Poly I:C. Total RNA was isolated from monocytes treated with different dosages of Poly I:C for 5 days. Real-time PCR was performed to determine the expression levels of CCR5 (A), IL-12 (B), ARG1 (C), and iNOS (D). Protein levels of Blimp-1, IRF5, TRAF2, and β-actin were determinate by western blot (E). Data are representative of three separate experiments (error bar represent SEM, ****p < 0.0001, as compared to non-treated control group, Student’s t-test).