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. 2016 Jun 29;55(37):11281–11286. doi: 10.1002/anie.201603738

Figure 5.

Figure 5

AdoRbl in a microbial bioassay. Application of vitamin B12 (CNCbl) to the plate promotes the growth of a S. enterica cbiB metE strain (A). AdoRbl on its own does not promote growth (B). Mixing AdoRbl with B12 results in increased growth circles that are noticeably less dense than the B12 growth halos (C, E, G). Addition of AdoRbl in close proximity to the point of application of B12 results in the appearance of a zone of inhibition that gets more extensive as more AdoRbl is added (D, F, H).