Table 1. LacZ mutant frequency in sperm collected 42 days after a 28-day exposure to benzo(a)pyrene, and clonal correction.
Dose (mg/kg bw/day) | Animal ID | Raw data |
Clonality |
Clonal correction |
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
MF × 10−5 | Average MF × 10−5 | SD | Fold change | % clonality | Average % clonality | Corrected MF × 10−5 | Average MF × 10−5 | SD | Fold change | ||
0 | 1 | 1.6 | 3.9 | 1.8 (46.2%) | — | 56.8 | 41.0 | 0.7 | 2.3 | 1.2 (52.2%) | — |
2 | 4.6 | 14.3 | 3.9 | ||||||||
3 | 4.7 | 58.5 | 2.0 | ||||||||
4 | 2.5 | 40.6 | 1.5 | ||||||||
5 | 3.3 | 26.8 | 2.4 | ||||||||
6 | 6.7 | 49 | 3.4 | ||||||||
100 | 7 | 13.4 | 13.1 | 3.4 (26.0%) | 3.4 | 27.8 | 24.8 | 9.7 | 9.5 | 1.0 (10.5%) | 4.1 |
8 | 13.3 | 35.2 | 8.6 | ||||||||
9 | 11.2 | 17.2 | 9.3 | ||||||||
10 | 9.2 | 4.8 | 8.8 | ||||||||
11 | 18.4 | 39.1 | 11.2 |
MF: mutant frequency.
SD: standard deviation.