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. 2016 Nov 10;16:199. doi: 10.1186/s12886-016-0373-3

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Effect of 100 nM BK on Akt and Erk1/2 phosphorylation in RPE cells during different periods. a Western blotting results for Akt and Erk1/2 phosphorylation during different periods. b Akt phosphorylation levels increased most significantly after 1 min of BK stimulation. c/d Erk1/2 phosphorylation levels increased most significantly after 5 min of BK stimulation. *P < 0.05, ** P < 0.01, **** P < 0.0001 versus with 0 min