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. 2016 Nov 9;15:187. doi: 10.1186/s12934-016-0591-7

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Production of PM100117 (1) and PM100118 (2) biosynthesis intermediates 10–13 in glycosyltransferase gene mutant strains. UPLC analysis at 254 (a) and 216 nm (b) wavelength of metabolite production in S. caniferus GUA-06-05-006A wild-type and ΔgonG1, ΔgonG2, ΔgonG3and ΔgonG4 deletion mutants. NR: peak non-related to PM100117/18. c Chemical structure of various PM100117/18 analogues