Table 7.
Effect of FOM on blood parameters in acetaminophen induced toxicity in rat
| Treatment (mg/kg bw) | WBC (103/μl) | TLC (× 103/μl) | PLT (× 103/μl) | Lymphocytes (%) | Neutrophils (%) | Granulocytes (%) |
|---|---|---|---|---|---|---|
| Control (Saline) | 7.16 ± 0.20b | 5.31 ± 0.47c | 710.16 ± 10.64c | 37.15 ± 3.45c | 60.15 ± 3.20c | 9.57 ± 0.52e |
| AMP 750 | 5.62 ± 0.22a | 7.62 ± 0.25a | 865.21 ± 118.32a | 59.43 ± 1.53a | 35.52 ± 1.21a | 15.12 ± 2.01a |
| AMP + Sily 50 | 7.64 ± 0.14d | 5.11 ± 0.43c | 702.19 ± 4.01c | 40.75 ± 2.15c | 62.83 ± 0.52c | 11.77 ± 0.84d |
| AMP + FOM 200 | 7.44 ± 0.45c | 6.51 ± 0.75b | 706.51 ± 56.36c | 47.18 ± 2.11b | 41.38 ± 1.90b | 11.29 ± 2.18d |
| AMP + FOM 400 | 7.82 ± 0.54d | 5.63 ± 0.12c | 843.15 ± 23.17b | 39.26 ± 1.22c | 58.71 ± 0.95c | 14.53 ± 0.33b |
| FOM 400 | 7.58 ± 0.29c | 5.10 ± 0.19c | 708.16 ± 7.89c | 34.11 ± 1.28c | 63.43 ± 1.18c | 12.93 ± 0.31c |
Mean ± SEM (06). Means with different superscript letters (a-e) within the column indicate significant difference (p <0.05). AMP, acetaminophen; FOM, F. olivieri methanol extract