Table 8.
Effect of F. olivieri on liver marker enzymes in acetaminophen induced toxicity in rats
| Treatment mg/kg bw | AST (U/l) | ALT (U/l) | ALP (U/l) | LDH (U/l) | Total bilirubin (mg/dl) |
|---|---|---|---|---|---|
| Control (Saline) | 31.90 ± 2.31d | 25.93 ± 5.11d | 158.65 ± 3.00d | 53.21 ± 1.46d | 1.18 ± 0.17c |
| AMP 750 | 71.49 ± 2.98a | 67.99 ± 3.01a | 325.11 ± 2.80a | 86.52 ± 1.58a | 2.16 ± 0.64a |
| AMP + Sily 50 | 63.24 ± 1.23b | 54.87 ± 2.67a | 231.42 ± 2.12b | 59.38 ± 1.34c | 2.08 ± 0.12a |
| AMP + FOM 200 | 53.71 ± 2.09b | 46.78 ± 1.76b | 187.64 ± 2.45c | 71.69 ± 2.03b | 1.82 ± 0.45b |
| AMP + FOM 400 | 44.39 ± 2.31c | 38.75 ± 2.45c | 146.73 ± 1.91d | 56.03 ± 1.32c | 1.29 ± 0.58c |
| FOM 400 | 35.30 ± 1.22d | 27.33 ± 0.91d | 142.19 ± 2.28d | 51.84 ± 1.11d | 1.25 ± 0.13c |
Mean ± SEM (06). Means with different superscript letters (a-d) within the column indicate significant difference (p <0.05). AMP, acetaminophen; FOM, F. olivieri methanol extract