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. 2016 Nov 10;11:129. doi: 10.1186/s13000-016-0579-y

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Integrated network among transcription factors, microRNAs and differentially expressed genes. Rhombuses represent microRNAs, triangles represent transcription factors and circles represent differentially expressed genes. Red represents up-regulation while green represents down-regulation. –—, interactions between differentially expressed genes; −—|, regulatory effects of microRNAs on differentially expressed genes; →, regulatory effects of transcription factors on differentially expressed genes