Table 5.
The top 5 significantly enriched GO_BP terms of screened modules
| Term | Count | Gene lists | P-Value | Adjusted P-value |
|---|---|---|---|---|
| Module 1 Score: 7.75 | ||||
| GO_BP: 0006955 ~ immune response | 4 | GPR183, PTPRC, NCF4, GPR65 | 2.35E-03 | 3.251619 |
| GO_BP: 0030097 ~ hemopoiesis | 3 | GPR183, PTPRC, PLEK | 4.34E-03 | 5.921337 |
| GO_BP: 0048534 ~ hemopoietic or lymphoid organ development | 3 | GPR183, PTPRC, PLEK | 5.25E-03 | 7.113787 |
| GO_BP: 0002520 ~ immune system development | 3 | GPR183, PTPRC, PLEK | 5.89E-03 | 7.959213 |
| GO_BP: 0001775 ~ cell activation | 3 | GPR183, PTPRC, PLEK | 6.36E-03 | 8.562876 |
| Module 2 Score: 6.333 | ||||
| GO_BP: 0048066 ~ pigmentation during development | 5 | DCT, SOX10, TYRP1, TYR, GPR143 | 1.07E-11 | 1.10E-08 |
| GO_BP: 0043473 ~ pigmentation | 5 | DCT, SOX10, TYRP1, TYR, GPR143 | 3.26E-10 | 3.35E-07 |
| GO_BP: 0046148 ~ pigment biosynthetic process | 4 | DCT, TYRP1, TYR, GPR143 | 8.84E-08 | 9.07E-05 |
| GO_BP: 0042440 ~ pigment metabolic process | 4 | DCT, TYRP1, TYR, GPR143 | 1.37E-07 | 1.41E-04 |
| GO_BP: 0042438 ~ melanin biosynthetic process | 3 | DCT, TYRP1, TYR | 1.84E-06 | 0.001882 |
Note: GO gene ontology, BP biological process. Count, the number of differentially expressed genes enriched in the corresponding term. The gene symbols were listed in accordance with the Gene database at NCBI (National Center for Biotechnology Information, http://www.ncbi.nlm.nih.gov/gene/?term)