Table 4.
All LMIC | Male (n) | Female (n) | ≤12a | df | I 2 (%) | 13–35a | df | I 2 (%) | 36–59a | df | I 2 (%) | 60–108a | df | I 2 (%) | Overall | df | I 2 (%) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Model 1 | 186,452 | 283,811 |
1.42 (1.25–1.63)
p=0.002 |
15 | 57.5 |
1.39 (1.23–1.57)
p=0.000 |
13 | 70.1 |
1.36 (1.22–1.52)
p=0.000 |
14 | 66.7 |
1.62 (1.46–1.80)
p=0.000 |
21 | 74.8 |
1.46 (1.38–1.56)
p=0.000 |
66 | 75.2 |
Model 2 | 175,554 | 266,621 |
1.42 (1.25–1.63)
p=0.002 |
15 | 57.5 |
1.40 (1.38–1.56)
p=0.000 |
12 | 72.3 |
1.37 (1.22–1.53)
p=0.000 |
13 | 69.1 |
1.62 (1.46–1.80)
p=0.000 |
21 | 74.8 |
1.47 (1.38–1.56)
p=0.000 |
64 | 75.9 |
Model 3 | 119,470 | 168,465 |
1.42 (1.25–1.63)
p=0.002 |
15 | 57.5 |
1.43 (1.24–1.64)
p=0.000 |
11 | 70.8 |
1.46 (1.21–1.75)
p=0.000 |
10 | 72.3 |
1.49 (1.35–1.54)
p=0.006 |
14 | 54.2 |
1.44 (1.35–1.54)
p=0.000 |
53 | 62.7 |
Model 4 | 86,233 | 117,719 |
1.42 (1.21–1.67)
p=0.002 |
12 | 60.7 |
1.48 (1.23–1.78)
p=0.027 |
5 | 60.4 |
1.50 (1.18–1.91)
p=0.000 |
8 | 77.8 |
1.49 (1.29–1.71)
p=0.005 |
13 | 56.8 |
1.46 (1.35–1.59)
p=0.000 |
41 | 63.4 |
Model 5 | 85,552 | 116,994 |
1.44 (1.22–1.71)
p=0.000 |
11 | 63.0 |
1.48 (1.23–1.78)
p=0.000 |
5 | 60.4 |
1.54 (1.18–2.02)
p=0.002 |
7 | 80.6 |
1.49 (1.29–1.71)
p=0.000 |
13 | 56.8 |
1.47 (1.35–1.60)
p=0.000 |
39 | 64.8 |
Model 6 | 85,431 | 116,756 |
1.37 (1.20–1.56)
p=0.000 |
10 | 43.9 |
1.48 (1.23–1.78)
p=0.000 |
5 | 60.4 |
1.54 (1.18–2.02)
p=0.002 |
7 | 80.6 |
1.43 (1.27–1.61)
p=0.000 |
12 | 42.2 |
1.43 (1.33–1.55)
p=0.000 |
37 | 58.9 |
df, degrees of freedom; LTFU, lost to follow-up; HR, hazard ratio.
Model 1: all HRs.
Model 2: high-quality studies only (7–9 stars).
Model 3: HRs with LTFU <18%.
Model 4: HRs with LTFU <15% (all also scored high on the NOS).
Model 5: HRs with LTFU <15% and adjusted for age (excludes n=2 HRs).
Model 6: HRs with LTFU <15%, adjusted for age, and accounts for potential publication extremes on the funnel plot (excludes two additional HRs beyond Model 5).
Months since initiation of ART