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Concentration-dependent effects of MPP+ on the cell viability of primary astrocyte cells. The cells were treated with 0, 50, 100, 200, 400, 800 or 1,200 µM MPP+ for 24 h, and the cell viability was determined using MTT assays. Absorbance was measured using a microplate reader. Data are presented as the mean ± standard error of the mean of five experiments. *P<0.05 vs. the untreated controls. MPP+, 1-methyl-4-phenylpyridinium.
