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. Author manuscript; available in PMC: 2017 Sep 8.
Published in final edited form as: Cell. 2016 Sep 8;166(6):1471–1484.e18. doi: 10.1016/j.cell.2016.07.029

Figure 7. Selected IGHV1-2*02/IGKV3-20*01 IgGs cloned from the stepwise immunized mice neutralized the same viruses sensitive to the corresponding mouse sera.

Figure 7

Neutralization IC50 and IC80 of the 27 IgGs against Env-pseudoviruses 45-01dG5, 426c, the mutant 426c viruses lacking 1, 2 or all 3 glycans at aa 276, 460 and 463, and 247-23 were listed. The presence (+) or absence (−) of N276/460/463 glycans in each pseudovirus is indicated. The neutralizing titers of VRC01 were shown as positive controls.