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Effect of KXS on cell survial and BDNF release from primary hippocampal neurons. (A) For cell viability assay, cells were treated with 25 pg/l BDNF or 50, 100 and 200 µg/ml of KXS for 48 h. **P<0.01 vs. the control group. (B) In the BDNF release test, cultured cells were treated with 100 µg/ml KXS for 0, 3, 6, 12, 24 and 48 h. **P<0.01 vs. the 0 h group. Data are presented as the mean ± standard deviation. KXS, Kai-Xin-San; BDNF, brain-derived neurotrophic factor; OD, optical density.
