Table II.
Animal group | Prior to administration | 8 weeks post-administration | 12 weeks post-administration | P-value |
---|---|---|---|---|
Beagle with ON of LM group | 2.7±0.3 | 4.7±0.2a | 4.8±0.3a | <0.05 |
Beagle without ON of LM group | 2.5±0.4b | 2.6±0.4a,b | 2.4±0.3a,b | >0.05 |
Control group | 2.6±0.3b | 2.5±0.3a,b | 2.4±0.3a,b | >0.05 |
P>0.05 vs. pre-administration in LM group
P<0.05 vs. control group post-administration.