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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1991 Feb 15;88(4):1466–1468. doi: 10.1073/pnas.88.4.1466

Localization and quantitation of tritiated compounds in tissue sections with a gaseous detector of beta particles: comparison with film autoradiography.

E Tribollet 1, J J Dreifuss 1, G Charpak 1, W Dominik 1, N Zaganidis 1
PMCID: PMC51039  PMID: 1996346

Abstract

Quantitative analysis of tritium polymer standards and of brain sections labeled with tritiated vasopressin was carried out by using a gaseous detector of beta particles designed for this purpose. The gaseous detector showed major advantages compared with film autoradiography: the linearity and the large dynamic range of intensity measurements as well as the short time needed for data acquisition.

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Selected References

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