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. 2016 Sep 5;12(5):3081–3088. doi: 10.3892/ol.2016.5086

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Copyright: © Qi et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Survival analysis for mutant heteroplasmy. Overall survival time in patients with non-small cell lung cancer was significantly decreased in patients with a low mutant load of mitochondrial DNA (mtDNA) 10398 compared with patients with a high mutant load of mtDNA 10398. Median survival time: 22.5 vs. 28.7 months; χ²=5.656; P=0.017 (Kaplan-Meier analysis and log-rank test).