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. 2016 Aug 26;12(5):3208–3214. doi: 10.3892/ol.2016.5050

Figure 1.

Figure 1.

miR-148a is upregulated in osteosarcoma tissues and cell lines. (A) miRNA microarray analysis of paired osteosarcoma tissues and adjacent normal tissues. The three most upregulated and downregulated miRNAs identified in the analysis are indicated. (B) miR-148a expression was examined in osteosarcoma cell lines using RT-qPCR (**P<0.01). (C) In 92 paired clinical human osteosarcoma tissues and adjacent normal tissues, miR-148a expression was examined by RT-qPCR. Data are presented as the mean ± standard deviation (n=4) in cell lines, or as horizontal lines (median) with boxes (interquartile range) and whiskers (corresponding to the 2.5th and 97.5th percentiles) in human samples (*data out of scope). miR/miRNA, microRNA; RT-qPCR, reverse transcription-quantitative polymerase chain reaction.