Table III.

SOX2 expression level was an independent prognostic factor (COX multivariate regression analysis).

Factors	Relative risk (95% CI)	P-value
Gender (male/female)	0.795 (0.416–1.519)	0.487
Age (≥57/<57 years)	1.158 (0.668–2.006)	0.601
Pathological type (adenocarcinoma/adenosquamous carcinoma)a	1.325 (0.945–1.859)	0.102
T staging (T3/T2/T1)	1.610 (1.004–2.584)	0.048
N staging (N2/N1/N0)	2.036 (1.527–2.714)	<0.001
SOX2 expression (high expression/low expression)	0.380 (0.223–0.649)	<0.001

^a‘Adenocarcinoma’ includes adenocarcinoma cases and adenosquamous carcinoma cases (15).